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KMID : 1143120160060020105
Asia Pacific Allergy
2016 Volume.6 No. 2 p.105 ~ p.111
Knowledge, attitudes, and practices survey of drug allergy among healthcare practitioners in central China: a multicenter study
Wang Yin

Zhu Rongfei
Huang Nan
Li Wenjing
Yang Lin
Zhang Shucheng
Liu Guanghui
Abstract
Background
Drug allergy (DA) is one of the most important contributors to iatrogenic morbidity and mortality. Currently DA remains a major challenge for healthcare practitioners (HCPs).

Objective: To assess the knowledge, attitudes and practices of DA among HCPs in Central China.

Methods: A 25-item self-administered DA questionnaire were developed and applied in our study. The questionnaire covered 3 domains: knowledge, attitudes, and practice patterns. From July 2015 to October 2015, HCPs in 7 cities of Central China anonymously participated in the cross-sectional study.

Results: A total of 350 HCPs participated the study, 91 questionnaires uncompleted and 259 were analyzed. Among the respondents, 166 (64.1%) were doctors, 55 (21.2%) were nurses and 38 (14.7%) were medical students. The mean knowledge precision was 59.8%. HCPs agreed that drug induced immediate allergic reactions were IgE mediated (83.4%) and happened within 6 hours after drug administration (89.6%), and epinephrine was the first choice for drug induced anaphylaxis (79.5%). They also agreed that penicillin skin test was valuable to predict allergic reaction (88.4%). However, high proportion of HCPs (66.0%) believed glucocorticoids had an impact on drug skin test rather than antihistamines (4.2%), 47.1% never performed positive and negative control during skin test. More than 90% of the respondents would take patients' allergic history before drug administration, 98.8% agreed that they should receive advanced training of DA knowledge and practice.

Conclusion: The HCPs demonstrated a low level of knowledge regarding DA. Advanced education is urgently needed for better understanding and filling the gaps exist in knowledge and clinical practice of DA.
KEYWORD
Knowledge, Attitude, Practice, Drug allergy, Healthcare practitioner
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